Innovative Treatments. Quality Data.

The Macoupin Research Group’s mission is to provide patients with access to innovative treatments in a manner that protects human subjects and provides quality data to assess the risks and benefits of the specific treatment under investigation.

Toward that end, we are dedicated to performing the highest quality clinical research and are committed to upholding the following core values.

  • Beneficence - Risk is minimized and proportional to anticipated benefit

  • Justice - Benefits, and burdens are distributed fairly among different groups

  • Respect of Person - Maintenance of privacy and confidentiality as well as full informed consent

  • Excellence and accuracy in subject selection and data collection

  • Honesty and integrity in all activities

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Patient Visits:  over 45,000 encounters per year

Macoupin Family Practice Centers, LLP is a community-based private practice group that provides primary care services for patients of all ages.  The practice treats up to 200 patients each day and maintains an active primary care base of approximately 20,000 patients.

Clinical Research

All clinical research activities conducted by Macoupin Family Practice providers are centrally coordinated and managed by highly trained research staff within the Macoupin Research Group (MRG).  The MRG consists of a Principal Investigator, 2 Sub-Investigators and a Clinical Research Coordinator.  The MRG staff have extensive experience conducting Phase II-IV pharmacological trials as well as devise studies.  All research staff are trained in ICH/GCP guidelines. 

 

Research Staff:

Principal Investigator

Bruce Weber, M.D.

Sub-Investigators

Anastasia Dufner, MD

Morgan Grothaus, FNP-C

Jason Manthei, PA-C

Clinical Research Coordinator

Jennifer Swan, MPH

 

Trial Experience:  25+ trials

Last FDA Audit: n/a

Address:

Macoupin Research Group

715 W. Broadway, Gillespie, IL 62033

Phone:  217-839-4491

Fax:  217-839-5030

 MRG Standard Operating Procedures;

  • Standard Operating Procedures For SOPS

  • Adverse Event Reporting Procedures

  • Clinical Study Operations

  • Handling Clinical Trial Test Article

  • Coordinator Selection, Qualifications, Responsibilities, and Training

  • Data Management

  • Informed Consent

  • Investigator Agreements with Sponsors/CROs

  • Investigator and Sub-Investigator Selection, Qualifications, Responsibilities, and Training

  • Institutional Review Board Approval and Operations for Clinical Studies

  • Pre-Study Requirements

  • Protocol Handling, Review of Feasibility, and Approval

  • Quality Control

  • Subject Recruitment Methods

  • Regulatory Documentation/Essential Documents

  • Sponsor Interactions

  • Study Close-Out Activities

  • Study Confidentiality

  • Federal Food and Drug Administration (FDA) Audits

  • Handling Allegations of Misconduct and Fraud

  • Disaster Recovery Planning

 Research Facilities

Located 60 minutes east of St. Louis International Airport, our main clinic is a 6,000 square foot facility with nine exam rooms, a well-equipped laboratory for specimen processing, a secured investigational drug storage facility, specimen refrigerators, a -20o freezer for lab sample storage, dry ice processing, a state-of-the-art computer network with electronic medical records, a dedicated space for study coordinators and monitoring visits, fax access, copier access, high-speed internet, and ample space for study material.

Gillespie Family Practice Center

715 W. Broadway

Gillespie, IL 62033

Phone:  217-839-4491

Fax:  217-839-5030

Additional Facilities

To better serve our patient base, the Macoupin Research Group also has another 3,000 square foot facility, located twelve miles from our main facility:

 

Carlinville Family Practice Center

15574 Route 108

Carlinville, IL 62626

Phone:  217-854-4319

Fax:  217-250-2256

 

The Macoupin Research Group also has a smaller satellite office located at:

 

Mt. Olive Family Practice Center

115 North Poplar

Mt. Olive, IL 62069

Phone:  217-999-4751

Fax:  217-999-2317

 

Hospital Affiliation:  HSHS St. Francis Hospital

Our Research Staff

  • Bruce F. Weber, M.D., FAAFP

    • Principal Investigator

    • Geriatric Medicine Certified

    • Member of the Academy of Pharmaceutical Physicians and Investigators

    • Diplomat, America Board of Family Practice

    • American Academy of Family Physicians

    • Illinois Academy of Family Physicians

    • Certified Medical Director in Post-Acute and Long-Term Care

    • Member of the American Diabetes Association

    • Member of the American Association for Physician Leadership

  • Jason Manthei, PA-C

    • Sub-Investigator

    • American Academy of Physician Assistants

    • Illinois Academy of Physician Assistants

  • Morgan Grothaus, FNP-C

    • Sub-Investigator

    • American Academy of Nurse Practitioners

  • Jennifer A. Swan, MPH

    • Clinical Research Coordinator

    • Former FOX Commercial IRB Board Member